The epigenome integrates & records past, present, and future.

exposures, including smoking, viral infections, early-life adversity, pollution, and others.

current cellular state and gene expression

health trajectories and cell fate

We use it to measure and modify the ageing process.

Measure: quantifiable markers of disease risk and ageing.

Modify: leverage epigenome to modulate health trajectories and cell fates.

Research areas

Unlocking the epigenetic code

Our research investigates how the epigenome encodes biological experiences, how this encoding shapes stem cell function across tissues, and whether these mechanisms can be measured non-invasively and causally modulated to influence ageing and disease trajectories.

Active

Epigenetic memory and cellular ageing

Defining how DNA methylation encodes biological experience across tissues and stem cells.

Epigenomics Functional genomics Bioinformatics
Active

Precision biomarkers of biological vulnerability

Translating epigenetic memory into non-invasive biomarkers that capture vulnerability, resilience, and disease risk before clinical onset.

Biomarker development Translational research
Emerging

Epigenetic regulation of stem cell function

Using experimental systems to test whether epigenetic states causally influence stem cell behaviour and ageing.

Experimental models Genome engineering
Recent publications

Read recent publications co-authored by lab members

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Meet the team

Pushing the boundaries of geroscience

Our team of researchers brings together expertise from multiple disciplines to redefine how we leverage epigenetics in ageing research.

Principal Investigator

Dr. Chiara Herzog

Dr. Chiara Herzog

Leading research in epigenetics to transform how we understand and modulate ageing.

Epigenetics Biomarkers Ageing research

Students

Jordan Apostolov

Jordan Apostolov

Jordan is an undergraduate student working on large-scale data harmonisation and improvement of computational tools for ageing research.

Epigenetics Genomic medicine
Peter Brederlow

Peter Brederlow

Peter Brederlow is a visiting MSc student from the University of Tübingen, studying Bioinformatics

Epigenetics Bioinformatics

Alumni

Phoebe Bedford

July - August 2025, now finishing her BSc at Oxford

Ageing Research Epigenetics
Lab news & updates
Upcoming events & outreach

Stay connected with our research through talks, workshops, and other events.

1st Longevity Symposium @ Technical University Munich featured image

1st Longevity Symposium @ Technical University Munich

Dr. Chiara Herzog will talk about how to measure biological age.

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Dr. Chiara Herzog
Keystone: Aging: Immune Function and Organ Health featured image

Keystone: Aging: Immune Function and Organ Health

Dr. Chiara Herzog joins the Keystone Symposium on Aging - Immune Function and Organ Health to present work conducted at the University of Innsbruck.

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Dr. Chiara Herzog
GRC Systems Aging 2026 featured image

GRC Systems Aging 2026

Dr. Chiara Herzog joins the 2026 GRC Systems Aging Conference in Newry, Maine.

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Dr. Chiara Herzog

Contact Us

Location

Department of Twin Research & Genetic Epidemiology

St. Thomas' Hospital

Westminster Bridge Road

SE1 7EH

London

United Kingdom

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